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A 9-year-old girl has bruising noted on the extremities and back, reportedly recurrent for one month duration. Lab results show a Hgb 7.1 g/dL, Hct 22.8%, MCV 89 fL, platelet count 63,000/µL, WBC count 19,128/µL. BM biopsy shows 100% cellularity with replacement by primitive cells with large nuclei, delicate chromatin; indistinct nucleoli with scanty cytoplasm. These cells mark for CD10 (CALLA) antigen. Which of the following is the most likely diagnosis?

A bone marrow sample evaluated for a patient describes the following notes: Erythropoiesis decreased. Erythrocytic precursors show abnormal development; nuclear bridging and budding. Rare precursor cells show iron stores ringing the nucleus Which disorder is suggested?

The erythrocytic morphology in megaloblastosis is best characterized by:

Patients with acute promyelocytic leukemia often have which genetic abnormality?

Heinz bodies composed of:

A mature B cell would express which immunophenotype?

A patient has a WBC count of 250 × 109/L, and a peripheral blood smear contains many granulocytes and granulocytic precursors including 2% blasts. Pending further tests, which of the following neoplastic conditions is the most likely diagnosis?

During a discussion of RBC indices, a medical technologist of Cambodian origin mentioned that she had a history of mild anemia and microcytic red blood cells noted on laboratory testing from previous routine physicals. A more recent CBC showed the following results. TEST      RESULTSWBC      9.3 x109/LRBC       5.11 x1012/LHGB      10.0 g/dLHCT       31.8%MCV      69.6 fL MCH     22.5 pg MCHC   31.0 g/dLRDW     16.5PLT        351 x109/L Differential: Within normal limits, many target cells noted. What disorder is suspected?

You are performing a differential for a patient with absolute leukocytosis and lymphocytosis. The following peripheral blood picture under the microscope should prompt you to do which of the following?

Calculate and interpret the absolute and relative cell counts. WBC count: 42 x 109/L Differential: 40% segmented neutrophils 15% lymphocytes 1% basophils 9% monocytes 35% atypical lymphocytes