A 30-year-old male presents to the emergency department with…

A 30-year-old male presents to the emergency department with difficulty breathing and wheezing after exposure to pollen. His oxygen saturation is 92% on room air, and he is using accessory muscles to breathe. Arterial blood gas reveals mild hypoxemia. Pulmonary function tests show reduced airflow. Which of the following is the most likely cause of his low ventilation-perfusion (V/Q) ratio?

A patient in the Medical Intensive Care Unit (MICU) is diagn…

A patient in the Medical Intensive Care Unit (MICU) is diagnosed with sepsis and severe hypoxemia. After 17 days in the MICU, his condition has not improved, and a repeat chest X-ray shows significant changes in lung architecture with worsening gas exchange. Which of the following pathophysiological changes is most likely contributing to his ongoing hypoxemia at this stage?