A 7-year-old presents with a persistent cough lasting 3 week…

A 7-year-old presents with a persistent cough lasting 3 weeks. Parents describe sudden, repeated coughing fits followed by a high-pitched inspiratory “whoop.” The child often vomits after these coughing spells but has no fever. Which diagnosis is most likely?

A 7-month-old infant presents with developmental regression,…

A 7-month-old infant presents with developmental regression, increased startle response, and decreased motor skills. On exam, the child has hypotonia and a cherry-red spot on the macula. Family history reveals both parents are of Ashkenazi Jewish ancestry. Which of the following is the most likely diagnosis?