This question refers to tumor suppressor genes and oncogenes…

This question refers to tumor suppressor genes and oncogenes in cancer. a. What is the fundamental difference between the roles of oncogenes and tumor suppressor genes in cancer progression?b. Which type of gene (oncogene or tumor suppressor gene) does the “two-hit hypothesis” apply to and why?b. Which type of gene (oncogene or tumor suppressor gene) was discovered first, and what factors made this discovery possible earlier in cancer research?d. Provide an example of how both an oncogene and a tumor suppressor gene could work together to drive cancer progression in the same cell.

Acme Company’s direct labor costs are 45% of its total conve…

Acme Company’s direct labor costs are 45% of its total conversion costs. During the current year, Acme’s direct material costs are $180,000 and its manufacturing overhead costs are $68,200. What are the company’s direct labor costs? Round to the nearest whole dollar amount and do not enter a dollar sign or a decimal point (e.g., enter 89, not $89.00).