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Answer only one of the questions below, either 4 OR 5 (15 total points)   Question 4: Shyam Mohapatra –  How do macrophages kill their prey?  Provide two examples of macrophage products that play a pivotal role in this process. “Intracellular microbes or parasites have evolved, however, methods to overcome the ‘wrath’ of macrophage and have developed survival mechanisms’. Justify this statement with one example.    Question 5: Shyam Mohapatra – “All roads lead to Rome”. How does this statement apply to innate immunity? Provide examples using responses to bacteria and viruses that utilize a specific set of pattern recognition receptors.

Answer only one of the questions below, either 10 OR 11 (13 total points) Question 10: Bharadwaj(a) “8 pts” What are the characteristics of an antibody, and how do the various classes differ?(b) “7 pts” What regions of the immunoglobulin domain contribute to its complementarity-determining regions, and what is their function?   Question 11: BharadwajFor each pair of antigens listed below, indicate which is likely to be more immunogenic when injected into a mouse and why? Explain the types of antigenic determinants(a) “8 pts” Native Protein or heat-denatured protein(b) “7 pts” LPS (lipopolysaccharide) or hen collagen

A nurse performs a physical exam on a 75-year-old client admitted 33 days prior for bilateral pneumonia. Upon inspection of the client’s sacrum, the nurse notes intact skin with a blister present and partial- thickness loss of skin over the client’s sacrum. The nurse knows this would be classified as which stage pressure injury?

You want to withdraw $100,000 annually from your retirement account for 10 years during retirement. With an interest rate of 10%, how much money must be in your retirement account at the start of retirement to fund those annual withdrawals?

Your team is overseeing the renovation of your distribution center. As part of the renovation, a new piece of order packaging equipment is being purchased for $160,000. The expected life of the equipment is 8 years, with an expected salvage value of $70,000. The equipment has an annual maintenance cost of $10,000 and will increase revenue by $75,000 beginning in year 4. Draw the cash flow diagram for this equipment.

As the outside temperature increases, marathon runners need to drink ________ water.

The processes by which the body regulates heat production is

Sore tongue, inflammation of the skin, depression, confusion, and small pale red blood cells represent the deficiency symptoms of vitamin

The growing or shrinking of fat cells is influenced by

Mineral toxicity symptoms are likely to emerge from