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A 1-year-old girl presents with excessive bleeding after her first immunizations and frequent bruising. Laboratory tests reveal prolonged aPTT and low factor VIII levels.  What is the most likely diagnosis? 

A patient with severe burns over a large body surface area is at increased risk of infection. Which of the following best explains this increased risk?

A 55-year-old female is diagnosed with a type of cancer known for high rates of p53 mutations.  What is the role of p53 in normal cells, and how does its mutation contribute to cancer? 

A patient with recurrent bacterial infections is found to have a deficiency in complement protein C3. What is the consequence of this deficiency? 

A patient with acute inflammation shows increased fluid accumulation at the site of injury. What causes this increased fluid accumulation? 

Which cells release cytokines that stimulate further chemotaxis and promote bone marrow leukocyte proliferation? 

What is the role of T-helper cells in the activation of B cells? 

During an immune response, where do antigen-presenting cells (APCs) typically interact with T cells? 

A 30-year-old female with a deep vein thrombosis is started on anticoagulant therapy. The medication inhibits thrombin.  Which step in the clotting process is directly affected by this medication? 

Which immunoglobulin is the most abundant in the body?