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Which of the following is NOT a ‘dual address’ signaling pathway?

Ligand binding by GPCRs activates what intrinsic receptor activity?

This growth factor binds to Frizzled type receptors

Cytokine receptors are used by mammalian cells to communicate with their environment. Functionally, cytokine receptors operate much like tyrosine kinase receptors, with some differences. Name two differences.

Define Loss of Heterozygosity (LOH) and briefly indicate a general example in which LOH would be detrimental to a person.

Which of the following lines of evidence supports the conclusion that cancer cell phenotypes are recessive?

RB inhibits passage through the R point in the cell cycle when it is hyperphosphorylated.

[A] are enzymes that covalently attach methyl groups to DNA at [B] dinucleotide sequences.

Select each true statement regarding the consequence of Rb binding to E2F.

The levels of pRB protein vary significantly throughout the cell cycle