A 40-year-old previously healthy man has the sudden onset of…

A 40-year-old previously healthy man has the sudden onset of severe right flank pain that comes in waves all night long. When he is seen in the emergency room, after waiting for two hours, he is exhausted. On physical examination there are no abnormal findings. Urinalysis reveals no ketones, glucose, protein, nitrite, or urobilinogen, but blood is present. Urine microscopic examination shows many RBCs but few WBCs. The specific gravity is 1.015 and the pH is 5.5. Which of the following is the most likely diagnosis?

A 29-year-old woman has experienced urinary frequency with d…

A 29-year-old woman has experienced urinary frequency with dysuria for the past 4 days. On physical examination she has no flank pain or tenderness. A urinalysis reveals sp. gr. 1.014, pH 7.5, no glucose, no protein, no blood, nitrite positive, and many WBC’s. She has a normal serum creatinine of 0.9 mg/dL. Which of the following is the most likely diagnosis?

A double blind study is conducted involving men who have bee…

A double blind study is conducted involving men who have been symptomatic from urinary frequency and hesitancy for 5 or more years. One group men receive a pharmacologic agent designed to reduce the synthesis of dihydrotestosterone in prostatic stromal cells. Another group receives a placebo. The group receiving the drug has a statistically significant decrease in symptoms. Which of the following enzymes is this pharmacologic agent most likely to block?