BCH4024 91824 OC F24 E1 Q43: Considering the enzyme reaction…

BCH4024 91824 OC F24 E1 Q43: Considering the enzyme reaction given. Where E = enzyme, S=substrate, P = product, Km = Michaelis constant, Kd = dissociation constant, Vo = initial velocity, Vmax = maximum velocity, [S] = substrate concentration, and [P] = substrate concentration). Which of the following statements is TRUE when k -1 >> k2?

You are administering heparin and following the protocol bel…

You are administering heparin and following the protocol below for a client weighing 189 lbs. The order is to administer an initial heparin bolus IV followed by a titrated IV infusion. Round to the tenths place. HEPARIN PROTOCOL Initial bolus- 50 units/kg Initial rate – 18 units/kg/h Obtain a PTT every 6 hours, and adjust dosage and rate as follows: If  PTT is less than 35 secs:      Repeat bolus with 80 units/kg and increase the rate by 4 units/kg/h If  PTT is 36 to 44 seconds:       Repeat bolus with 40 units/kg and increase the rate by 2 units/kg/h If  PTT is 45 to 75 seconds:       Continue current rate. If  PTT is 76 to 90 seconds:       If  PTT is 76 to 90 seconds:          Decrease rate by 2 units/kg/h If  PTT is greater than 90 secs: Hold the heparin for 1 hour and decrease rate by 3 units/kg/h Available (for bolus)  – heparin 1,000 units/mLAvailable (for infusion) –  heparin 25,000 units in 250 mL D5W    How many mL will the client receive for the repeat heparin IV bolus in response to the PTT of 40 secs?