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(Teng, 3 pts). Lifelong infection by herpesviruses is facilitated by their ability to regulate several cellular processes. List AT LEAST 3 potential cellular pathways regulated and discuss.

What is the main reason for a carotid artery ultrasound?

(Porterfield, 4 pt) Discuss the use of pseudoviruses as a way to increase the safety of working with retroviruses in the lab and two specific strategies used to make them more safe. Also discuss at least one limitation of using these constructs.

When conducting a systematic review, describe WHY determining the risk of the bias of included studies is important

(Teng, 4 pts). Describe the lytic replication of a herpesvirus.  

James is a 16 y/o male (he/him) who sustained a concussion while playing ice hockey. His main goal for PT is to return to playing hockey in time for the championship game next month. You educate him that in order for him to return to playing in a hockey game, he needs to:

A network meta-analysis comparing the likelihood of various classes of antihypertensive medications and the development of depression was conducted. Below is the table of direct and indirect comparisons from the network meta-analysis. Which comparison is an example of incoherence?

(Teng , 2 pts) Herpesviruses are unique in that the virions include a tegument layer. Tegument proteins have functions in _________________ and ____________________. 

Guselkumab was compared to placebo for the treatment of ulcerative colitis in a randomized double-masked controlled trial. At the end of the trial, participants who received guselkumab were 15% more likely to be in remission from their ulcerative colitis (p=0.003). What type of statistical error is the study at risk for?

The following figure is from a systematic review of observational studies of middle and high school students. It comparing those who used e-cigarettes to those who did not for their risk of asthma. Interpret the results of the forest plot.