A 60-year-old man with chronic alcoholism and a 20-pound wei…

A 60-year-old man with chronic alcoholism and a 20-pound weight loss over 2 months is admitted with pneumonia. He has had minimal oral intake for 10 days. Enteral nutrition is initiated at full caloric requirements. Within 48 hours, he develops confusion, muscle weakness, and arrhythmias. Labs: phosphate 1.1 mg/dL, potassium 2.8 mEq/L, magnesium 1.0 mg/dL.Which of the following best explains his clinical decline?

A 72-year-old woman with advanced chronic kidney disease is…

A 72-year-old woman with advanced chronic kidney disease is admitted for evaluation of altered mental status. Her laboratory results reveal a total serum calcium of 8.2 mg/dL (reference range: 8.5–10.5 mg/dL), albumin of 2.0 g/dL (reference range: 3.5–5.0 g/dL), and ionized calcium of 1.10 mmol/L (reference range: 1.20–1.40 mmol/L). Which of the following statements best describes the physiological significance of her calcium results?

The AGACNP is evaluating a patient in the ED with chronic lo…

The AGACNP is evaluating a patient in the ED with chronic low back pain and considering additional pharmacologic treatment prior to discharge. Balancing control of a patient’s chronic pain with prevention of potential opioid overdose is important. Which of the following is true? 

A 78-year-old woman is admitted for acute heart failure exac…

A 78-year-old woman is admitted for acute heart failure exacerbation. Over the past 48 hours, her weight has increased by 2.5 kg. On examination, she has elevated jugular venous pressure, bilateral lower extremity pitting edema, and rales at the lung bases. Her vital signs are: BP 110/70 mm Hg, HR 98 bpm, RR 22/min, SpO₂ 94% on room air. Urine output has decreased to 0.4 mL/kg/hr. Which of the following findings is the most specific clinical indicator of fluid overload in this patient?

A 64-year-old man with diabetes and chronic kidney disease i…

A 64-year-old man with diabetes and chronic kidney disease is brought to the ED with confusion and Kussmaul respirations. He has been on metformin therapy. Vitals: BP 88/54, HR 118, RR 28, SpO₂ 95% on room air. Labs: Na 138 mEq/L, K 5.5 mEq/L, Cl 102 mEq/L, HCO₃ 12 mEq/L, BUN 48 mg/dL, Cr 3.2 mg/dL. Arterial blood gas: pH 7.21, PaCO₂ 25 mmHg. Lactate is 8 mmol/L.Which of the following is the most likely underlying cause of his metabolic acidosis?