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In a tightly coupled mitochondrial electron transport system, inhibition of electron transport at complex III will be accompanied by accumulation of the oxidized form of which of the following reductants? ElectronTransport2(1).png 

Given that all phosphotransferases have similar catalytic mechanisms, consider the half-reactions for the uncatalyzed transfer of inorganic phosphate from 1,3-BPG to ADP. One half-reaction produces water and the other consumes water. Observe that the phosphoglycerate kinase (PGK)-catalyzed phosphoryl transfer from 1,3-BPG to ADP does not include water. Select the best explanation for why the catalyzed reaction does not include water. uncatalyzed half-reaction 1 1,3-BPG + H2O → 3BPG + Pi uncatalyzed half-reaction 2 ADP + Pi → ATP + H2O PGK-catalyzed coupled reaction 1,3-BPG + ADP → 3PG + ATP

The exergonic flow of electrons from NADH catalyzed by Complex I is sufficient to drive which of the following endergonic processes? 

The isocitrate dehydrogenase-catalyzed citric acid cycle reaction has a ∆Go’ of -8.4 kJ mol-1 and information in the Bx resource,isocitrate + NAD+ → α-ketoglutarate + CO2 + NADHSelect the value in kJ mol-1 that is closest to the ∆Go’ for the uncatalyzed half-reactionisocitrate → α-ketoglutarate + CO2 + 2e-

Malate dehydrogenase catalyzes the following reaction in the citric acid cycle (ΔGo’= +29.7 kJ mol-1).malate + NAD+ → oxaloacetate + NADHMatch each half reaction with its correct thermodynamic nature of the reaction.

Identify the subcellular location where activated electron carriers are produced by the given enzymes. Answer choices: Cytoplasm Outer mitochondrial membrane Inner mitochondrial membrane Mitochondrial matrix Pathway Enzyme Reducing equivalent Subcellular location Pyruvate dehydrogenase NADH [BLANK-1] Citric acid cycle Isocitrate dehydrogenase NADH [BLANK-2] Citric acid cycle/electron transport Succinate dehydrogenase FADH2 [BLANK-3] Electron transport Complex I QH2 [BLANK-4]

Hydrolysis of which bond releases the most energy in physiological conditions? phosphoBonds.png 

Given the Gibbs free energy equation in the Bx resource, the reaction catalyzed by phosphoglycerate kinase, its ΔGo’, and its ΔG under typical physiological conditions, 1 , 3 – B P G + A D P ⇄ 3 P G + A T P Δ G 0 ‘ = 18 . 8   k J · m o l – 1 Δ G = 1 . 3   k J · m o l – 1 identify each statement as True or False. [BLANK-1]  The reaction is near equilibrium under physiological conditions. [BLANK-2]  ΔG is the determining factor for whether the reaction is near or far from equilibrium. [BLANK-3]  Elevating the concentration of ATP will accelerate the forward reaction. [BLANK-4]  At equilibrium, the product of the concentrations of 3PG and ATP will equal the product of the concentrations of 1,3BPG and ADP.

Identify the form of NAD+/NADH and its subcellular location that needs to be maintained in order to sustain anaerobic glycolysis in skeletal muscle during intensive exercise.

A technician says he needs to provide power to an older IDE hard drive and a DVD-ROM in a desktop. The computer has a new fully modular power supply. The technician wants to know what type of power connector he should use. SATA SCSI USB Molex