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Synapsin proteins are used in which stage of synaptic transmission?

The nAChR channel you are studying has an ERev of 0 mV, under normal conditions. You decide to experimentally DECREASE the OUTSIDE concentration of K+. What change in ERev would you expect to see? Assume ACh binds the receptor and no other changes are made in the cell. 

When D1 and D2 act as a heterodimer, they couple to ___. This leads to downstream activation of ____. 

Post-synaptic changes in Vm directly trigger the release of neurotransmitters. 

CASE STUDY (#24-28): Cameron is a 7 year-old girl who has an obvious petechial rash, along with other bleeding symptoms. Her physician orders coagulation screening tests, and here are the results: Platelet Count – 276,000/μL             PT – 12 seconds;              aPTT – 27 seconds  The physician decided to order platelet aggregation studies.  Results from the platelet aggregation studies were as follows:ADP –abnormal 2nd wave (normal 1st wave)        Collagen–abnormal        Epinephrine–abnormal 2nd wave (normal 1st wave) Ristocetin-normal What do Cameron’s platelet aggregation study results indicate?

Calcium current required to release synaptic vesicles is…

Select the Platelet Aggregation results that would be likely in a:  Normal Patient on Aspirin

Which of the following is a way to reduce the harm caused by glutamate excitotoxicity? 

Suppose a person presents to a hospital with muscle weakness, drooping eyelid, and nystagmus. After several tests, it is determined that this person is suffering from Myasthenia gravis – an autoimmune reaction that reduces the number of nicotinic acetylcholine receptors (nAchRs). Which of the following medications would be expected to BEST HELP this person’s condition? 

CASE STUDY (#29-33).  Nina is a 15-year old girl who reports to the Doctor for her annual sports physical.  Upon physical analysis, the physician notes pinpoint, purplish spots on Nina’s forearms and calves.  When questioned, Nina states that she has had quite a few bloody noses recently, too. The physician orders a panel of hemostatic screening tests on Nina.  Here are the results:Platelet Count – Normal               PT – Normal               aPTT – Normal Platelet Aggregation Studies and Urea Solubility are done on Nina’s sample.  Here are the results:ADP – Normal                  Epinephrine – Normal                   Collagen – Normal             Ristocetin – Abnormal Urea Solubility – Clot present after 24 hours Based on all of the lab testing results and patient symptoms, what would be the most likely specific cause of Nina’s symptoms?