A 22-year-old man with a known history of sickle cell diseas…

A 22-year-old man with a known history of sickle cell disease; presents to the emergency department with severe pain in his chest and back that started suddenly in this exercise. He describes the pain as sharp and throbbing, and he rates it as a nine out of 10 on the pain scale. The patient appears pale and is visibly distressed. He has a low-grade fever and exhibits signs of dehydration. What are the hallmark symptoms of sickle cell crisis that the healthcare team should be aware of in managing this patient?