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What is the primary role of chemotactic factors in acute inflammation? 

A 70-year-old female with a history of osteoporosis presents with severe hip pain after a minor fall. X-rays reveal a hip fracture.  What is the underlying condition that increased her risk of fracture? 

What type of force typically causes damage to the medial collateral ligament (MCL) of the knee? 

A 35-year-old female with a family history of breast cancer is found to have a germline mutation in the BRCA1 gene, a tumor suppressor gene.  What is the significance of this mutation for her cancer risk? 

Which of the following substances is released by activated platelets to recruit more platelets to the site of injury? 

What is the main difference between sporadic and hereditary cancers? 

A patient who recovered from a previous infection has a rapid and robust immune response upon re-exposure to the same pathogen. Which cells are responsible for this enhanced response in humoral immunity? 

What happens to osteoblasts after they have completed forming new bone tissue? 

A 60-year-old male with a history of chronic lower back pain presents with worsening symptoms. He reports numbness and weakness in both legs. MRI reveals multiple herniated discs in the lumbar spine.  What is the most likely explanation for his worsening symptoms? 

Which of the following best describes the pathogenesis of lateral epicondylitis?