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For each of the following sentences, fill in the blanks with the best word or phrase selected from the list below. Not all words or phrases will be used; each word or phrase should be used only once.

When visualized using the electron microscope the appearance of ‘rough’ endoplasmic reticulum results from the presence of which protein complexes?

Which type of movement is the least common for lipids in a bilayer?

Which type of movement is the least common for lipids in a bilayer?

Select the most appropriate description of the targeting signaling responsible for directing protein transport to each intracellular compartment listed below. Targeting SignalA. ER import signal: [A]B. mitochondria targeting signal: [B]C. nucleus localization signal: [C]

Briefly describe how cholesterol changes the properties of a biological membrane.

Predict what would happen to secreted proteins if signal peptidase was inactivated in a cell. In your answer, be sure to state where you anticipate the protein will be found and why?

Predict what would happen to secreted proteins if signal peptidase was inactivated in a cell. In your answer, be sure to state where you anticipate the protein will be found and why?

Briefly describe how cholesterol changes the properties of a biological membrane.

Briefly describe the underlying defect that occurs in epidermolysis bullosa patients that causes their skin to be more prone to blistering. For full credit, your description must include the name of the mutant protein, its normal function in cells, and how mutations in the protein can result in blistering.