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A 7-year-old child presents with fatigue, pallor, and growth…

A 7-year-old child presents with fatigue, pallor, and growth delay. The CBC and peripheral smear results are as follows: WBC Count: 25.0 x 10⁹/L RBC Count: 5.8 x 10⁶/µL Hemoglobin (Hgb): 6.5 g/dL Hematocrit (Hct): 19% MCV: 65 fL MCH: 18 pg MCHC: 30 g/dL RDW: 16.1% Platelet Count: 450 x 10⁹/L NRBCs: 35 per 100 WBCs Peripheral Smear Findings: Microcytic, hypochromic RBCs. Target cells, anisocytosis, poikilocytosis, and basophilic stippling. Numerous NRBCs. Based on the laboratory data and peripheral smear findings, what is the next best step in the workup of this sample?  

Puberty What are Kisspeptin and KNDy neurons and what ro…

Puberty What are Kisspeptin and KNDy neurons and what role do these neurons play in regulating GnRH secretion and onset of puberty? A 17-year-old female long-distance track star at a local high school has failed to obtain puberty. She visits you, a world-renowned reproductive endocrinologist, to determine the cause of the delay.  A physical is performed and it was discovered that she has an extremely low BMI (body mass index) and approximately 5% body fat.  Explain to your patient a potential cause for this delay.