A ligand, L, binds non-covalently to the active site of an e…

A ligand, L, binds non-covalently to the active site of an enzyme with a dissociation constant, Kd, of 1 nM. When a different type of ligand, X, is bound non-covalently to a different site in the enzyme the ligand L binds non-covalently to the active site of the enzyme with a Kd of 1 µM. The effect exerted by X on the binding of L to the enzyme is an example of:

An antibody binds specifically to a small, monomeric globula…

An antibody binds specifically to a small, monomeric globular protein only when the small protein is in its denatured (i.e. unfolded) state; the antibody does not bind when the small protein is in its native (i.e. folded) state. Given only this information and what you know about the structure and properties of the amino acids, which of the following amino acids is most likely to be found in the epitope recognized by the antibody?