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The cellular alteration shared by most all tumors and cancer is:

Match each of the items with the correct type of tissue:

Describe the expected negative feedback regulation of blood calcium in a person that is not consuming enough calcium in their diet. Be sure to identify the sensor/receptor, controller, and effectors in your answer.

Explain the mechanisms needed for your body to heal cut or damaged skin including the specific steps needed to repair, regrow, and rebuild the damaged dermis AND epidermis layers.

Match the cell indicated in the bone diagram with the correct answer:

Identify the injury shown in image A: [a1]  The joint involved in the injury, image A: [a2] Identify the injury shown in image B: [b1] The joint involved in the injury, image B: [b2]

These are BONUS QUESTIONS. You can answer any that you choose, but make sure you have already completed the real exam questions first! What is the BRAF gene and why is the BRAF V600E mutation important? Describe the relationship between the genes MGMT or PRAME and cancer risk: Describe the specific cellular changes triggered by active Vitamin D3 binding to its receptor in target cells: Describe how bisphosphonates work compared to Xgeva (denosumab): Describe how monoclonal antibodies such as Cemiplimab (Libtayo®) can help fight cancer: Predict how autografts of perichondrium might be useful surgically: Explain the severity of these injuries to a friend or colleague: MCL sprain/partial tear, Meniscus tear, Articular cartilage loss on the tibial plateau: Is there something else I forgot to ask you related to this Unit? Then explain any such topic(s) here and tell me what else you know:

The layer of skin that contains many thick fibers of extracellular matrix and is responsible for the bulk of the skin’s strength is the:

Cancers are commonly derived from epithelial tissue since most epithelia are:

Explain why basal cell carcinoma is almost never a deadly cancer and why melanoma is sometimes a deadly cancer; be sure to accurately describe invasion AND metastasis in your answer while discussing EACH of these cancers: