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The most important risk factors for the development of neonatal sepsis are low birth weight and prematurity. 

Small for gestational age babies tend to have a lower level of red blood cells. 

Newborns have a relatively higher CO,  lower SVR and lower BP when compared to an older child.  

Management of hyperbilirubinemia is often more complex in the term and late preterm infant. 

Infants with acyanotic heart disease may be asymptomatic immediately after birth. 

In a hypovolemic infant, BP often declines after acidemia and hypoxemia are corrected. 

Gas trapping can be prevented during mechanical ventilation by allowing for an appopriately long expiratory time. 

Sepsis causes the body’s normal reaction to infection to go into overdrive. 

Phototherapy should not be interrupted with the mother is visiting baby. 

CPAP should be initiated in full term infants with >40% O2 requirements and irregular respirations.