An 84-year-old female is brought to the Emergency Department…

An 84-year-old female is brought to the Emergency Department by ambulance for intermittent fevers over the last two days. A caretaker at her nursing home reports that the patient has had new-onset incontinence and foul-smelling urine during the past week. They also state that the patient has been more confused than usual during this time. She has a medical history significant for Alzheimer dementia, hypertension, diabetes mellitus, and hyperlipidemia. Her temperature is 98.6°F (37°0F), pulse is 96, blood pressure is 90/60 mmHg, respirations are 24/min. Laboratory studies are obtained and demonstrate a leukocyte count of 11,500. Which of the following aspects of this patient’s presentation meets criteria for the systemic inflammatory response syndrome (SIRS)?