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PS is a 52 yo female status post total hysterectomy and double oophorectomy. She has no significant cardiovascular medical history, and her only medication is gemfibrozil (Lopid) 600mg bid for hypertriglyceridemia. She comes to the clinic with complaints of night sweats, hot flashes every 20 minutes, and vaginal irritation with sexual intercourse. Which is the BEST menopausal hormone therapy option?

The acute pediatric pain patient should be treated with the following hierarchy of treatments:

A 55-year-old female with a history of chronic kidney disease presents with fatigue and pallor. Her hemoglobin is 9.0 g/dL, and her serum ferritin is 10 ng/mL. She weighs 60 kg. The patient is currently on a regimen of darbepoetin 500 mcg SC every three weeks. The decision is made to initiate parenteral iron therapy. Which of the following is the most appropriate treatment plan for this patient?

A 28-year-old female presents to the clinic with complaints of feeling on top of the world for the past week. She reports sleeping only 2-3 hours each night but feels fully rested. Her husband reports that she has been spending excessively and has been more talkative than usual. Her past medical history is notable for episodes of severe depression. On examination, her mood is elevated, and speech is rapid with flight of ideas. Her thought process is goaldirected, and no hallucinations or delusions are noted. Which of the following is the most appropriate medication for this patient?

Which route of administration is rapid with water soluble drugs, slow with poorly soluble drugs, but easily crosses capillary wall?

Lactulose’s mechanism of action in pediatric constipation is:

BJ is a 55 yo female with a uterus and ovaries. She is experiencing night sweats, hot flashes, and vaginal dryness. The night sweats are causing palpitations leading to insomnia. Which of the following is most appropriate for menopausal hormonal therapy would be appropriate for BJ? 

A 26 yo male in your care has been diagnosed with major depression syndrome. You wish to start him on pharmacologic therapy, but he expresses significant concern regarding sexual side effects. Which of the following depression medications is an option that will reduce the risk of sexual dysfunction?

A 10-year-old African American boy with a known history of sickle cell disease presents to the emergency department with sudden abdominal pain and distension. His mother reports that he has been lethargic and pale for the past few hours. On examination, he is tachycardic, hypotensive, and has a markedly enlarged spleen. Laboratory tests reveal a significant drop in hemoglobin and platelet count. The patient is admitted for a splenectomy and stabilization of his sickle cell disease. Which of the following treatments will lower fetal HgbF, decrease mortality and morbidity, and decrease hospitalizations by 50%?

What Supreme Court case outlawed segregation in schools?