Select the most appropriate description of the targeting sig…

Select the most appropriate description of the targeting signaling responsible for directing protein transport to each intracellular compartment listed below. Targeting SignalA. ER import signal: [A]B. mitochondria targeting signal: [B]C. nucleus localization signal: [C]

Briefly describe the underlying defect that occurs in epider…

Briefly describe the underlying defect that occurs in epidermolysis bullosa patients that causes their skin to be more prone to blistering. For full credit, your description must include the name of the mutant protein, its normal function in cells, and how mutations in the protein can result in blistering.

Use the RAN cycle diagram below to answer the following ques…

Use the RAN cycle diagram below to answer the following questions. A. What is nucleotide-bound state of RAN (1)? [A]B. What is the subcellular location of RAN (2)? [B]C. In which nucleotide-bound state does RAN have a higher affinity for the nuclear import receptor? [C]