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A 29-year-old pregnant woman (16 weeks gestation) has schizophrenia controlled on haloperidol. She asks whether she should stop it. What should you recommend?

Which of the following adverse effects is most associated with D2 blockade in the nigrostriatal pathway?

A 45-year-old man with schizophrenia taking clozapine for 8 months presents with fever and sore throat. His WBC is 2,500/µL and ANC is 900/µL. What should the ARNP do next?

What is the most concerning adverse effect of lamotrigine?

Which of the following atypical antipsychotics acts as a partial agonist at D2 receptors?

What is the mechanism of action of lithium in the treatment of bipolar disorder?

A 35-year-old woman with schizophrenia is prescribed aripiprazole. She asks how this medication differs from others.Which of the following best explains its pharmacologic mechanism?

A 37-year-old man with bipolar disorder is prescribed a mood stabilizer that works by increasing brain concentrations of GABA, blocking voltage-gated sodium channels, goes by the brand name Depakote, and inhibiting T-type calcium channels. Which medication fits this description?

A 28-year-old man with schizophrenia is started on haloperidol. Which of the following best describes the mechanism of action of haloperidol?

There are 20 multiple-choice questions (7 pts each) and 3 scenario-based questions (20 pts each).Midterm #1 should be taken sometime between 9:30 am on 10/16 (Thu) and 11:59pm on 10/19 (Sun).You may access downloaded class materials and class-related websites (such as Connect or Blackboard) during the exam. This means you do not need to pre-download all class materials.Microsoft Excel and Word programs are allowed. However, online versions (e.g., Google Sheets, Google Docs) are not permitted.External websites such as ChatGPT, Google, or Gemini are strictly prohibited during the exam.Your exam monitor will be recorded and thoroughly reviewed by me and the TA afterward. Any suspicious activity during the exam will result in a score of zero.If your exam session is not properly recorded, you will be required to retake the exam under my supervision.Online students: Dual-monitor usage is not allowed. All activities must be recorded on a single monitor.The exam will automatically submit 80 minutes after you begin.Relax. As one of my mathematics instructors 15 years ago once told our class: “Tests are teaching tools. Part of an exam is for me (the instructor) to see what you know, but a more important objective is that it provides a way to get you (the student) to study. Even if you make a (potentially big) mistake on an exam, you’re unlikely to forget it, and this is an opportunity for learning. That’s what school is all about.”Good luck everyone!