A 22-year-old woman presents with primary amenorrhea and cyc…

A 22-year-old woman presents with primary amenorrhea and cyclic pelvic pain. Physical exam reveals a shortened vagina and no visible cervix. Imaging confirms a hypoplastic uterus and obstructed vaginal canal. On further history, the patient reports that her mother took a nonsteroidal estrogen during early pregnancy. Which of the following medications is most likely responsible for this patient’s congenital anomaly?

A 6-month-old infant presents with an abnormally elongated a…

A 6-month-old infant presents with an abnormally elongated and narrow skull. On exam, the anterior fontanelle is closed, and there is a palpable ridge along the midline of the skull. CT confirms early fusion of a midline calvarial suture. Which suture is prematurely fused, and which bones are involved?