What post translational modification is required for the sel…

What post translational modification is required for the selective transport of lysosomal proteins from the TGN to the lysosome? (1pt) In the absence of this modification, where would these proteins localize? (1pt)  Explain why they would localize here.  (1pt)

In mammalian cells, the accumulation of misfolded proteins i…

In mammalian cells, the accumulation of misfolded proteins in the ER results in the activation of three parallel pathways involved in mitigating defects associated with this event.  Identify by name, one of the ER transmembrane proteins that function as the ‘sensor’ for this pathway.