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A major area of inquiry in the engram research field is the degree to which the neural ensembles or circuits that join specific types of memories (e.g. fear versus reward) are predetermined or flexible. Consider the relevant evidence from the lecture to answer the following questions. Be sure to describe the neural manipulation(s), and the behavioral and/or neural outcome measurement(s) that support your answers for each part.  Is it possible to change which neurons join an engram in the amygdala during initial fear conditioning? Does the evidence supporting your answer suggest these neurons are necessary for the expression of the associated memory? (4 points) Is it possible to change which neurons join an engram in the hippocampus during initial fear conditioning? Does the evidence supporting your answer suggest these neurons are necessary for the expression of the associated memory? (4 points) Can the “valence” of an amygdala engram be switched from negative to positive, or vice versa, after the engram has been established? (4 points) Can the “valence” of a hippocampal engram be switched from negative to positive, or vice versa, after the engram has been established? (4 points) What do any differences between the flexibility of hippocampal and amygdala engrams suggest about the different roles these regions play in memory formation and expression? Is any of the evidence you discussed contradictory? (4 points)

Match the design concepts with their definitions:

If a list a = [4, 5, 6] is cloned as b = a[:], and a.append(7) is executed, what is the length of b?

Which of the following best distinguishes composite volcanoes from shield volcanoes?

A country with a TFR of 1.3 and an aging population is most likely in which stage?

Which of the following best describes a functional region?

Fully describe the methods used to process EMG data and control for EMG confounding including: 1) how was emg voltage converted to all positive values? 2) what are the 3 primary confounders of EMG and how did you control for them? 3) what was the normalization process and final units of measurement?

The boundaries of perceptual regions, like “the South” or “the Heartland,” are shaped more by cultural understandings than measurable physical features.

James is a 48 year old male who is recovering from a heart attack (acute myocardial infarction) for which antiplatelet activity, routinely clopidagrel, is indicated.  His CYP2C19 genotype is *1/*1 (extensive metabolizer).  Which of the following adjustments should be made to his regimen?

When factory personnel are responsible for production planning and the organizations wants to minimize their interactions with the ERP system, this is characterized by?