Which of the following electrical instruments shows the relationship between a circuit’s true power and apparent power?
Blog
The conclusion of the funeral process and assisting the fami…
The conclusion of the funeral process and assisting the family with a sense of closure is what stage of the Helping Matrix?
Which of the following correctly describes the regulatory me…
Which of the following correctly describes the regulatory mechanisms affecting glycogen synthase activity?
Which one of the following amino acids contains an amine gro…
Which one of the following amino acids contains an amine group on the side chain?
Brown adipose tissue (BAT) is specialized in thermogenesis,…
Brown adipose tissue (BAT) is specialized in thermogenesis, the production of heat, to maintain body temperature in response to cold exposure. Unlike white adipose tissue (WAT), which primarily stores energy in the form of triglycerides, BAT contains abundant mitochondria and is highly vascularized, making it metabolically active. The thermogenic activity of BAT is attributed to the presence of uncoupling protein 1 (UCP1), also known as thermogenin, which is embedded in the inner mitochondrial membrane. Thermogenin functions by uncoupling oxidative phosphorylation. Instead of allowing the proton gradient generated by the electron transport chain (ETC) to drive ATP synthesis, UCP1 facilitates the flow of protons back into the mitochondrial matrix, dissipating the gradient as heat. This process is activated in response to norepinephrine signaling, which triggers lipolysis and the release of free fatty acids that activate UCP1. The role of BAT and UCP1 extends beyond thermoregulation; studies suggest that BAT activity may improve metabolic health by increasing energy expenditure, making it a potential therapeutic target for obesity and metabolic disorders. However, excessive or uncontrolled activation of BAT thermogenesis may pose risks, such as increased oxidative stress or wasting of metabolic substrates. Which of the following best describes the primary role of thermogenin (UCP1) in brown adipose tissue?
Acetyl-CoA carboxylase activity is likely to increase under…
Acetyl-CoA carboxylase activity is likely to increase under which of the following conditions?
What is the best analytical technique to detect and quantify…
What is the best analytical technique to detect and quantify a complex mixture of compounds in biofluids?
Which of the following is the most appropriate treatment app…
Which of the following is the most appropriate treatment approach for managing diabetic ketoacidosis (DKA)?
Which of the following statements about the electron transpo…
Which of the following statements about the electron transport chain and the proton gradient depicted in the image is correct?
Which one of the following is NOT an anaplerotic reaction?
Which one of the following is NOT an anaplerotic reaction?