A 30-year-old woman is brought to the emergency department w…

A 30-year-old woman is brought to the emergency department with signs of morphine overdose. Talking to her friend, you discover that she had self-administered morphine 6 h ago. You order a blood analysis which reveals the morphine blood level to be 0.25 mg/L. Assuming that the Vdof morphine in this patient is 250 L and the half-life is 3 h, how much morphine did she inject 6 h earlier?

When looking at the Noyes Whitney equation we can see that w…

When looking at the Noyes Whitney equation we can see that when oral medications are taken, smaller particles can increase the surface area which increases the dissolution rate (dC/dt) of the drug. This increases the absorption. Which one of these also cause an increase in the dissolution rate?