Given the vo vs. S plots below for an enzyme in the presence…

Given the vo vs. S plots below for an enzyme in the presence or absence of a competitive inhibitor, Enter True or False for each of the following statements. CompetitiveInhibition.png ​Prompt ​Response ​The K M a p p of the inhibited enzyme is larger than the KM of the uninhibited enzyme because the KM of the inhibited enzyme has changed. ​[BLANK-1] ​Addition of more inhibitor will not change the K M a p p of the inhibited enzyme. ​[BLANK-2] ​The vo at saturating substrate concentration will be the same for the inhibited and uninhibited reaction. ​[BLANK-3] ​Using one-half the concentration of inhibitor will increase the vo at saturating substrate concentration. ​[BLANK-4]

The imidazole side chain of the hemoglobin beta chain residu…

The imidazole side chain of the hemoglobin beta chain residue His-β146 has a pKa of 7.9 when in the T state (shown below). Determine how its ionization state will change and how it will affect its interaction with the Asp-β94 side chain as the pH shifts from 7.2 in the muscle to 7.4 in the lungs. Enter Increase, Not change, or Decrease. 1b86.png ​Prompt ​Response ​His-β146 imidazole ionization state will ​[BLANK-1] ​His-β146 imidazole interaction with Asp-β94 side chain will ​ [BLANK-2]