Which of the following would DECREASE membrane potential (Vm…

Which of the following would DECREASE membrane potential (Vm)? Consider any decrease, regardless of magnitude.  Assume the ‘normal physiological’ physiological conditions and: EK+ = (-)70 mVENa+ = (+)50 mVECl- = (-)65 mVECa+2 = +120 mVVrest = (-)60 mVThreshold = (-)40 mV HINT: think about the Goldman equation and the fact that you are starting at Vrest. (select all that apply)

The proposed cause of CJD and kuru in humans, mad cow diseas…

The proposed cause of CJD and kuru in humans, mad cow disease, and scrapie in sheep is a change in a brain protein. Disease victims appear to have a protein that should normally contain alpha helices but instead they have changed into a protein made of beta pleated sheets. Which level of protein structure is associated with these diseases?