A new antihistamine, metalazine, is compared to placebo for…

A new antihistamine, metalazine, is compared to placebo for mild-to-moderate seasonal allergies. An allergy symptom visual analog scale of 0, meaning no symptoms, to 10, meaning the worst symptoms imaginable is used as the primary outcome. Metalazine was found to decrease the allergy symptoms visual analog scale by 3.2 points (95%CI -0.4 to 7.8). Which of the following statements best describes the potential type of statistical error present in this study?

A study compares is determining the impact of daily consumpt…

A study compares is determining the impact of daily consumption of green tea on systolic blood pressure. Among patients who began drinking green tea daily (n=23) the systolic blood pressure decreased by a mean of 5 mmHg and among patients with no dietary change (n=32) the systolic blood pressure decreased by a mean of 1 mmHg. Which of the following tests would be most appropriate to determine if the results are statistically significantly different?

Melatonin is compared to placebo for sleep in a single-group…

Melatonin is compared to placebo for sleep in a single-group randomized cross-over study (n=328). Participants are randomized to receive melatonin or placebo for 3 months and then take the other agent for 3 months following a 1-week washout period. Which of the following tests would be most appropriate to determine if this is a statistically significant difference in mean sleep latency (i.e., mean minutes to fall asleep)?