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Discuss the concept of negative feedback as it relates to the regulation of hormone secretion. Use two examples from the body during exercise to support your answer. 

A 50-year-old female with a family history of breast cancer is found to have a mutation in the BRCA1 gene, a tumor suppressor gene.  What is the most likely consequence of this mutation? 

An older adult with hyperthyroidism is experiencing atrial fibrillation. How does thyroid hormone affect cardiovascular activity?

The process of breaking down glycogen into glucose is called , while the process of synthesizing new glucose from other substrates is called . 

The posterior pituitary gland contributes to fluid regulation via secretion of . 

A bodybuilder consumes a high-protein meal, leading to elevated amino acid levels in the blood.  What is the effect of increased amino acids on insulin secretion? 

release is proportional to exercise intensity and notably contributes to growth of tissues, organs, and muscle. 

Which condition exacerbates the tendency for bone resorption in postmenopausal women? 

A patient presents with symptoms of hyperthyroidism, including weight loss, palpitations, and exophthalmos.  What is the likely diagnosis and underlying mechanism?

What is the primary role of insulin in the body?