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A 72-year-old female presents with right upper quadrant pain and jaundice. Labs show elevated bilirubin and alkaline phosphatase. What is the most likely cause?

A 60-year-old female with a recent diagnosis of breast cancer is found to have a BRCA1 mutation. What is the implication of this genetic finding?

A 65-year-old woman with diabetes presents with proteinuria and hypoalbuminemia. What structural change in the nephron is most responsible?

A 28-year-old woman presents with fatigue, facial puffiness, and frothy urine. Her blood pressure is elevated, and labs show hypoalbuminemia and hyperlipidemia. What syndrome is most likely?

A nurse dissolves TWO prednisolone 5mg soluble tablets in 20mL of water.     What is the prednisolone concentration in mg/mL of the resulting solution? Give your answer to ONE (1) decimal place.

Recently published data shows that the prevalence of asthma in patients over 18-years-old is 1 in 20 and the prevalence of COPD in patients over 18-years-old is 1 in 32. Your surgery has 8,000 registered patients over the age of 18 years.   How many more patients aged over 18 would you expect to have asthma compared to the number who have COPD?

A 5-year-old child, who weighs 18.2kg, was admitted to hospital requiring fluid and electrolyte replacement. They are prescribed sodium chloride 0.18% and glucose 4% at a dose of 3mmol/kg to be given intravenously over 24 hours.   What is the infusion rate in mL/hour required to deliver the prescribed dose? Give your answer to the nearest whole number.   Extract from Online BNF for intravenous fluids

You are a foundation trainee who is running an event on salt content of OTC medicines. Co-codamol 8mg/500mg soluble tablets contain 19.1mmol of Na+ per tablet. The maximum recommended daily allowance (RDA) of salt for an adult is 6g (2.4g of sodium) per day. The atomic mass of sodium is 23. If an adult patient took two co-codamol soluble tablets, what percentage of their maximum recommended daily salt allowance would they have consumed? Round your answer to the nearest whole number.

A four-year-old patient who weighs 16.8kg is prescribed dexamethasone for croup. The standard dose is 150microgram/kg for one dose.    How many mL of dexamethasone 2mg/5mL liquid should be prescribed for this patient?   Give your answer to ONE (1) decimal place. 

A 25-year-old patient, who weighs 120kg, is admitted to a critical care unit. As part of their treatment, dexmedetomidine is prescribed for sedation at a dose of 700nanograms/kg/hour.  The infusion is prepared by diluting 20mL of dexmedetomidine 100micrograms/mL to 250mL in sodium chloride 0.9%w/v.    What is the correct infusion rate in mL/hour to administer the prescribed dose?  Give your answer to ONE (1) decimal place.