A client presents with progressive fatigue, pruritus, and ab…

A client presents with progressive fatigue, pruritus, and abdominal distention. The nurse notes 2+ bilateral lower extremity edema, multiple spider-like vascular lesions on the chest, and yellowing of the sclera. Laboratory results show elevated bilirubin, low albumin, and prolonged PT/INR. Based on these assessment findings, the nurse suspects impairment of which organ system?