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After giving birth, a 30-year-old woman developed heat intolerance and loses more weight than expected postpartum.  On physical exam, her thyroid is enlarged but painless.  Lab studies show increased serum T4 and low TSH level.  A year later, she is euthyroid.  Which of the following is most likely to be the pathogenesis of this patient’s disease?

Zollinger-Ellision syndrome can be part of MEN-1 sydrome

A 28-year-old, otherwise healthy man has had headaches for the past 2 weeks.  His blood pressure is measured as 174/116 mm Hg.  A right adrenalectomy is done and the gross photo is shown as below.  Which of the following lab findings in his blood is most likely reported before surgery?

A 50-year-old man with fasting blood glucose > 150 mg/dL on two occasions and is put on a restricted caloric diet and started on oral medications to reduce blood glucose.  Which of the following lab test is most likely to be the best to monitor disease control in this man?

For the patient in previous question, what type of the cells is the mass composed of?

A 25-year-old woman has noted breast secretions for the past month.  She is not breastfeeding and has never been pregnant.  She has not menstruated for the past 5 months.  MRI of brain shows a 0.7 cm mass within the sella turcica.  Which of the following additional complications is she most likely to have?

These adrenal neoplasms are composed of chromaffin cells, which synthesize and release catecholamines and in some instances peptide hormones. They are a rare cause of surgically correctable hypertension.

Which of the followings is not part of hypothalamus-pituitary-endocrine organ pathways?

This signaling pathway in cell growth is commonly seen in tissue repair, in which the cells produce the ligand act on adjacent cells.

A 41-year-old woman notices that her gloves from previous winter no longer fit her hands.  Her facial features have become coarse and her voice seems deeper in the last year.  Lab studies indicate high levels of fasting serum glucose (138 mg/dL) and hemoglobin A1C (8.6%).  Which of the following additional test result is most likely to indicate the cause of her physical and lab findings?