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BCH4024 OC F25 E3 Q11: A healthy boy was born uneventfully to apparently normal parents. Delayed acquisition of motor skills was suspected by 3 months of age. At 12 months of age, involuntary twisting and stiffening movements emerged. At 3 years of age, he began to chew on the inside of his lip and occasionally on his index finger. Elevated levels of uric acid were also found in a blood test. The child diagnosis is ______________________ and results from a deficiency in the activity of ________________?

BCH4024 OC F25 E3 Q50: A consequence of chronic liver cirrhosis (liver damage) is the deposition of excess fat in the liver causing further liver damage (fatty liver syndrome). The failure to produce which of the following plasma lipoproteins would prevent lipids from being exported from the liver and thus leading to the buildup of liver fat?

BCH4024 OC F25 E3 Q28: Which of the following enzymes assimilates free ammonia?

BCH4024 OC F25 E3 Q38: What is the role of the enzyme-bound PMP in transamination?

BCH4024 OC F25 E3 Q46: A 41-year-old man presented to his primary care physician after he noted a 20-minute episode of blurred vision in his right eye. Laboratory findings included blood plasma total homocysteine at 28 uMol/l (normal: 5-12 uMol/l) and methionine at 43 micromol/l (normal:16-30 uMol/l). In this patient, supplementation of which cofactor would directly reduce homocysteine levels?

BCH4024 OC F25 E3 Q24: A 45-year-old man has elevated LDL cholesterol and a family history of early-onset coronary artery disease. Genetic testing reveals a mutation in the LDL receptor gene. Which apolipoprotein is required for LDL receptor binding?

Questions 32 & 33 deal with the following case: A 16-year-old boy with known type 1 diabetes presents with vomiting, abdominal pain, and rapid breathing. He missed his insulin doses for two days. Labs show: Blood glucose: 520 mg/dL Serum ketones: high Arterial pH: 7.10 Bicarbonate: low Plasma free fatty acids: elevated Urine glucose and ketones: positive BCH4024 OC F25 E3 Q33: What is the biochemical basis of the acidosis?

BCH4024 OC F25 E3 Q7: Which of the following best describes the role of trypsin in protein digestion?

BCH4024 OC F25 E3 Q5: Starting with free ammonium ions and the carbamoyl phosphate synthetase reaction, which of the following is CORRECT?

BCH4024 OC F25 E3 Q1: A person with phenylketonuria cannot convert__________ to__________?