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What is the difference between B-2 cells and B-1 cells?  Which group is TI and which is TD?

During T cell development, what does it mean when the thymocyte is double positive?

Name 4 of the 7 ways antibody diversity is generated. 

Ignoring cross presentation, indicate whether each of the cell components or processes listed is involved in the processing and presentation of exogenous (EX) antigen, endogenous (EN) antigen.

Kappa and lambda light-chain genes

Spleen cells are taken from a mouse immunized with the LCM virus.  2 assays are used to determine antigen-specific functional activity of the spleen cells.   Assay 1: the spleen cells (T cells) are incubated with macrophages that have been briefly exposed to LCM virus (phagocytized the virus), production of IL-2 by the T cells is considered a positive response. Assay 2: the spleen cells are incubated with LCM-infected target cells, lysis of the infected target cells is considered a positive response. Activity of which cell population is detected in Assay 1?

Give an example of a thymus-independent (TI) antigen:

What are high endotheilial venules (HEVs)?  Are they involved with lymphocyte or leukocyte extravasation?

In antibody gene rearrangement, what is allelic exclusion?

Where will a B cell mature?