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Refer to the following mRNA sequence: 5’…GGAGCUCGUUGUAUU…3’ Which amino acids does this sequence code for, if the reading frame is as shown, starting from the correct end?

What are some of the ethical considerations you would now take into account before getting direct-to-consumer genetic testing done? Provide two considerations. 1.   2.

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Direct-to-consumer genetic testing is different than medical genetic testing in that direct-to-consumer genetic testing provides access to one’s genetic information without the involvement of a medical professional or health insurance company. 

What is the type of genetic test that is used to detect changes in embryos created using assisted reproductive techniques such as IVF?

When sending your saliva in to a direct-to-consumer genetic testing company they will perform [1] to look for genetic variants, which requires prior identification of variants of interest and is [2] for companies because it only looks at very specific places in the DNA. The genetic health risk report will determine your [3] which is the increased likelihood of developing a particular disease based on your genetic makeup. Having an increased genetic risk for a disease means that you will [4] be affected by that disease in your lifetime. The [5] will use DNA sequence polymorphisms whose allele frequencies are significantly different in populations from different geographical regions of the world to determine your ancestry. 

Describe the Central Dogma of Genetics/Biology and include in this description how mutations lead to genetic diseases and disorders. 

Which of the following correctly describes genotyping instead of sequencing?

[1] are when a DNA segment of one kilobase or larger is present at a variable copy number in comparison to the reference genome, and encompass [2] nucleotides per genome than SNPs and are [3] likely to cause health problems than SNPs. Common CNV’s in humans are [4] such as Huntington’s disease and spinocerebellar ataxia. Huntington’s disease is caused by a trinucleotide repeat [5] the coding sequence of the gene, while Fragile X syndrome is caused by a trinucleotide-repeat in the [6] region of the gene. The proposed mechanism for trinucleotide-repeat diseases is [7] which is thought to happen more often in regions of repeat during the process of [8].

In 2008, researchers discovered a genetic mutation in a man that took place 6,000-10,000 years ago. He that is thought to be the first person to have the mutation that resulted in blue eyes, and would therefore be the source of all blue-eyed humans alive on the planet today.