A 45-year-old man presents with progressive clumsiness, stat…

A 45-year-old man presents with progressive clumsiness, stating he often drops objects and recently has had difficulty performing tasks requiring fine motor coordination, such as hammering a nail. He also reports that his speech has become slurred, and his legs occasionally feel weak. He denies visual or cognitive changes. A chronic degenerative disease of the central nervous system involving predominantly motor neurons is suspected. Which of the following is the most likely diagnosis?

A 40-year-old administrative assistant presents with daily h…

A 40-year-old administrative assistant presents with daily headaches that she describes as a dull, pressure-like pain around the forehead and occipital area. The pain is bilateral, non-pulsatile, and is not associated with nausea, vomiting, photophobia, or aura. She notes that the headaches often begin in the afternoon and are worse during periods of stress. Over-the-counter analgesics provide some relief. What is the most likely patient’s diagnosis?