A child has disputed paternity. The child has the following…

A child has disputed paternity. The child has the following STR haplotype: TPOX = 7/8; D5S818 = 11/12; D13S317 = 9/10; vWA = 11/12; D21S11 = 27/28. Alleged Father 1 has the following STR haplotype: TPOX = 6/10; D5S818 = 9/13; D13S317 = 9/14; vWA = 14/16; D21S11 = 30/33. What can be said of Alleged Father 1?

A proficiency test (PT) composed of two frozen tissue specim…

A proficiency test (PT) composed of two frozen tissue specimens was received in the molecular laboratory. The specimens were to be tested for the detection of a gene mutation that is part of the laboratory’s current test menu. Because one technologist was off that day and the other staff members were occupied with a large number of patient samples, the supervisor decided to test the two specimens using a modified assay being developed in the laboratory. Because this method was in development, the results of the test were checked against sequencing analysis performed in a blinded manner at a partner institution. The results of the test were recorded on the proficiency documents, signed by the supervisor, and reported to the PT testing agency. When the report from the proficiency agency was received, the laboratory results were consistent with results from other participating laboratories. The laboratory director, however, refused to sign the results.  Why would the laboratory director not accept the proficiency test results?