The vast majority of pathogenic (disease-causing) single bas…

The vast majority of pathogenic (disease-causing) single base gene mutations result from G:C >>> T:A transition mutations, where the C is changed to a T. Discuss the following related to this anomoly: Why is this particular transition mutation so prevalent in the human genome? As discussed in class, which DNA repair pathways would logically attempt to prevent this mutation, and why would the repair fail at a higher rate than most other mutations?. Why is this particular transition mutation very rarely observed near the promotor regions of actively transcribed genes?  (hint: think DNA methylation)

Take photos of your result, clearly show the switches and th…

Take photos of your result, clearly show the switches and the 7-segment display. Embed all FOUR images for the FOUR possibilities of the switches, showing the letters ‘E’, ‘P’, ‘I’ and ‘C’. Notes: To prove originality of your work, you are required to write down your Name, Panther ID, date and time on a piece of paper and place it next to the BASYS3 board. You can embed one image at a time. To embed an image, click on the vertical three dots icon to expand toolbar, then…

Choose amongst any of the the various types of Next Gen Sequ…

Choose amongst any of the the various types of Next Gen Sequencing (NGS) technologies discussed in class and answer the following: Give an example of a ‘Biology question’ that a researcher can answer using your chosen NGS approach. Make sure it’s a complete thought/ sentence that ends with a ‘?’. Design and describe an experiment/ a logical scenario using NGS that would answer the question stated above… i.e. explain how the physicians or molecular geneticists would employ the particular NGS approach, and how the NGS data (alignment, coverage, etc.) would answer the question being asked by the researchers.