In class we discussed the paper, “Optogenetics enables funct…

In class we discussed the paper, “Optogenetics enables functional analysis of human embryonic stem cell-derived grafts in a Parkinson’s disease model”. The figures below come from that paper. (FYI: Halorhodopsin-EYFP is the same thing as eNpHR3.0-EYFP)   Match each panel (A, B, and C) with the mouse genotype that could be responsible for the data. 

Loss-of-function mutations in the SCN2A gene will most likel…

Loss-of-function mutations in the SCN2A gene will most likely cause autism/intellectual disability. 1) 1) This type of mutation will most likely [decrease] neuronal excitability. 2) If an individual with this type of mutation develops seizures, does it make sense to treat them with a sodium channel blocker? [no]

A patient diagnosed with lumbar spinal nerve root impingemen…

A patient diagnosed with lumbar spinal nerve root impingement has been referred to physical therapy.  The PT has indicated mechanical traction in the POC.  What is the lowest body weight that should be considered for the initial traction force for this patient?  ( patient wt. 220 pounds, split table)

A therapist elects to use a small set of electrodes when app…

A therapist elects to use a small set of electrodes when applying electrical stimulation to the anterior forearm of a patient rehabilitating from an upper extremity injury.  Which of the following is most accurate when comparing small electrodes to larger electrodes?