In this hypothetical scenario, a GWAS revealed 4 variants as…

In this hypothetical scenario, a GWAS revealed 4 variants associated with developing chronic obstructive pulmonary disease. Three individuals were genotyped at those 4 SNPs to calculate their PRS. Use the data below to calculate their PRS. Jake Emma Kiera Genetic Variant Effect allele Effect size Genotype Genotype Genotype rs1234 C 0.08 CC CT TT rs2345 T -0.12 TG TG TT rs3456 G 0.34 GA GG AA rs4567 A 0.04 AC AC AA