A 29-year-old woman presented to her primary care physician…

A 29-year-old woman presented to her primary care physician for a routine medical exam. She brought along her 3-year-old daughter as her husband had to work. The patient’s family history is unremarkable. Her personal history includes the one pregnancy and natural birth that had no complications.    Patient Results Reference Interval WBC 5.9 4.5-11.0 x 10^9/L RBC 4.64 4.3-5. x 10^12/L HGB 11.9 g/dL HCT 36.4 39-55% MCV 78.0 80-11 fL MCH 25.6 25.4-34.6 pg MCHC 32.7 31-37 g/dL RDW 14.3 11.5-14.5 % PLT 1362 150-400 x 10^9/L What is the differential diagnosis?

A 20-year-old woman with sickle cell anemia whose usual hemo…

A 20-year-old woman with sickle cell anemia whose usual hemoglobin concentration is 8g/dL develops fever, increased weakness, and malaise. The hemoglobin concentration is 4g/dL and the reticulocyte count is 0.1%. The MOST likely explanation for her clinical picture is: