BCH4024 F25 E2 Q11: Common genetic causes of severe adult ob…

BCH4024 F25 E2 Q11: Common genetic causes of severe adult obesity are loss-of-function mutations in the melanocortin signaling pathway. One effect of these mutations is aberrantly low levels of cAMP-dependent activated protein kinase A in certain cells of the hypothalamus. What type of mutation would most likely result in severe adult obesity?

BCH4024 F25 E2 Q1:  What hormone(s) would govern use of glyc…

BCH4024 F25 E2 Q1:  What hormone(s) would govern use of glycogen stores in skeletal muscles when frontier settlers spent long days walking and riding horseback over the Appalachian Mountains during which time a minimal amount of food was consumed as they were traveling in fear?

BCH4024 F25 E2 Q6:  A 3 day-old male infant has poor feeding…

BCH4024 F25 E2 Q6:  A 3 day-old male infant has poor feeding, decreased muscle tone, and several seizures per day. Lab tests show elevated levels of lactate, massive elevations of fumarate, and decreased levels of malate. You suspect a problem with the citric acid cycle.  What enzyme deficiency would most directly lead to these lab test results?