A vaccine against a Salmonella pathogen includes a purified…

A vaccine against a Salmonella pathogen includes a purified bacterial protein combined with an aluminum salt adjuvant that helps promote activation and maturation of dendritic cells. Explain: a) why is the adjuvant important in this vaccine formulation and how does it enhances antigen recognition, presentation to T cells, and eventually improves antibody production by B cells? b) Where do Dendritic cells go after they mature, what type of MHC is involved and the type of T cell that is activated 

A 40-year-old patient is admitted to the hospital after a fa…

A 40-year-old patient is admitted to the hospital after a fall where they struck the front of their head forcefully on concrete. Witnesses report a brief loss of consciousness immediately after the impact. Upon regaining consciousness, the patient’s family notes a significant change in their behavior; they are uncharacteristically irritable, impulsive, and have difficulty concentrating or making simple decisions. Neurological examination reveals some subtle difficulties with fine motor tasks. Based on the likely area of impact (forehead) and the resulting symptoms described – changes in personality and mood, difficulty with decision-making and planning, and issues with voluntary movement control – which major division or lobe of the brain is most likely affected according to the information in the sources, and what specific functions of this area align with the patient’s presentation?