A number of mutations have been described in G proteins that…

A number of mutations have been described in G proteins that have profound effects on their activity. For example, some mutations greatly increase the affinity of the G protein for GDP, making it very difficult for GDP to be exchanged for GTP. Other mutations prevent the hydrolysis of GTP to GDP. For each of the statements that describes a malfunction in cellular response, indicate the type of mutation that is responsible. ​ The MAP kinase pathway is continually activated, even in the absence of a signaling molecule. Which type of mutation could be responsible for this malfunction in cellular response?

Consider the events that describe the progress of a protein…

Consider the events that describe the progress of a protein that will be secreted from the cell. 1. SRP (signal recognition particle) binds to the growing polypeptide chain and to the ribosome. 2. Translation resumes. 3. The ribosome and growing peptide move to the rough endoplasmic reticulum 4. Protein synthesis begins in the cytosol. 5. Translation pauses. ​ Which sequence of events correctly describes the progress of a protein that will be secreted from the cell?