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A postmenopausal woman presents with vaginal bleeding. Imaging reveals a large ovarian mass and her plasma CA-125 (a tumor marker) is elevated. A biopsy is planned, but the patient asks what the elevated CA-125 means. What is the best response? 

Which of the following best describes the sequence of events in the metastatic cascade? 

What would you expect to occur if a microRNA associated with APC is missing? 

In a twin study investigating asthma development, one twin is diagnosed with asthma, but the other is not. What term best describes this difference?    

Bilateral edema of the lower extremities is common as a result of hypoalbuminemia in chronic liver disease patients. Which of the following best describes the pathophysiological mechanism behind the edema?

Mutation of which proto-oncogene is a common driver mutation that can cause persistent PI3K/AKT and MAPK pathway activation and usually confers a poorer prognosis as compared to cancers without this mutation. 

Which of the following cells are NOT typically involved in a Type IV (4) hypersensitivity reaction? 

Which of the following best explains the mechanism of injury following reperfusion?

If a person inherits a mutated COL1A1 gene there is a 100% chance of developing osteogenesis imperfecta, also called brittle bone disease, however the clinical presentation can vary in severity. Which of the following best describes this phenomenon?

A church that has a prescribed order of worship and follows rubrics is considered to be: