A 52-year-old man arrives to the clinic for evaluation of ar…

A 52-year-old man arrives to the clinic for evaluation of arthritis and leg swelling. The patient reports that the joint pains began 8 months ago. He has tried acetaminophen and ibuprofen without significant improvement. He reports the leg swelling began within the past 2 months and has gotten progressively worse. The patient’s medical history is significant for diabetes. His medications include metformin and aspirin. The patient works as an accountant. He smokes cigars socially. The patient’s temperature is 99°F (37.2°C), blood pressure is 130/78 mmHg, pulse is 70/min, and respirations are 14/min with an oxygen saturation of 98% on room air. Physical examination notes a deeply tanned appearing, overweight male with 2+ edema of bilateral lower extremities. Which of the following tumor markers is associated with a known complication of this patient’s condition?