Blog

The absence of D-Dimers is useful in ruling out:

A 35-year old woman with neurologic symptoms presents with a markedly decreased platelet count. She has moderate anemia with many red cell fragments on the blood film as well as polychromasia and nucleated red blood cells. The PT and PTT are both normal. Which of the following is most likely?

What is the mechanism for the platelet dysfunction in multiple myeloma and Waldenstrom’s macroglobulinemia?

A 39-year old male patient shows evidence of poor wound healing and a history of joint bleeding. What protein deficiency is most likely?

What tests are best to distinguish thrombotic thrombocytopenic purpura from DIC when a patient has schistocytes?

Which British general was shot and killed at the Battle of Queenston Heights?

In class we discussed the paper, “Optogenetics enables functional analysis of human embryonic stem cell-derived grafts in a Parkinson’s disease model”. The figures below come from that paper. (FYI: Halorhodopsin-EYFP is the same thing as eNpHR3.0-EYFP)   Match each panel (A, B, and C) with the mouse genotype that could be responsible for the data. 

Loss-of-function mutations in the SCN2A gene will most likely cause autism/intellectual disability. 1) 1) This type of mutation will most likely [decrease] neuronal excitability. 2) If an individual with this type of mutation develops seizures, does it make sense to treat them with a sodium channel blocker? [no]

The figure below is the same figure as in the previous question.     Which bar denotes the behavior of a “diseased” mouse after receiving a transplant of dopamine cells that expressed Halorhodopsin and whose brain is being illuminated by 543 nm light?

A PTA is preparing mechanical traction for a patient with facet joint hypomobility in the lower lumbar spine. What duty cycle is MOST appropriate?