Platinum-based drugs are very effective at treating cancer,…

Platinum-based drugs are very effective at treating cancer, but they are also very toxic to non-cancerous cells as well. A recent study showed that platinum-based drugs affected the structure of the nucleus. Specifically, a region within the nucleus known as the nucleolus was damaged by these drugs.  This is noteworthy because the nucleolus is the area where the parts of ribosomes are made.  What process would be directly disrupted by the failure to make ribosomes?