BCH4024 OC F25 E3 Q46: A 41-year-old man presented to his pr…

BCH4024 OC F25 E3 Q46: A 41-year-old man presented to his primary care physician after he noted a 20-minute episode of blurred vision in his right eye. Laboratory findings included blood plasma total homocysteine at 28 uMol/l (normal: 5-12 uMol/l) and methionine at 43 micromol/l (normal:16-30 uMol/l). In this patient, supplementation of which cofactor would directly reduce homocysteine levels?

Questions 32 & 33 deal with the following case: A 16-year-ol…

Questions 32 & 33 deal with the following case: A 16-year-old boy with known type 1 diabetes presents with vomiting, abdominal pain, and rapid breathing. He missed his insulin doses for two days. Labs show: Blood glucose: 520 mg/dL Serum ketones: high Arterial pH: 7.10 Bicarbonate: low Plasma free fatty acids: elevated Urine glucose and ketones: positive BCH4024 OC F25 E3 Q33: What is the biochemical basis of the acidosis?

BCH4024 OC F25 E3 Q3: A 45 year-old male was diagnosed with…

BCH4024 OC F25 E3 Q3: A 45 year-old male was diagnosed with advanced squamous cell carcinoma of the head and neck. A combined therapy using both radiation and chemotherapy was recommended. The chemotherapy included 1000 mg/m2/day IV of Fluorouracil (5FU) over a 4-day period. Why is 5FU included in this patient’s chemotherapy?